JNJ-79635322

Phase 1, First-in-Human, Dose Escalation Study of JNJ-79635322, a Trispecific Antibody, in Participants With Relapsed or Refractory Multiple Myeloma or Previously Treated AL Amyloidosis

  • Myeloma Service

What's the purpose of the trial?

The primary purpose of this study is to identify the recommended phase 2 dose (RP2D\[s\]) and schedule(s) to be safe for JNJ-79635322 in Part 1 (dose escalation), and to characterize the safety and tolerability of JNJ-79635322 at the RP2D(s) selected and in disease subgroups in Part 2 (dose expansion).
Trial status

Accepting patients

Phase
Phase 1
Enrollment
180
Last Updated
1 week ago
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Participating Centers

There are 9 centers participating in this trial. Enter a location below to find the closest center.

Experimental Treatments

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  • JNJ-79635322 is a trispecific antibody that targets BCMA and GPRC5D on cancer cells, and CD3 on our own immune cells.

Arms / Cohorts

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Accepting patients

Dose Escalation

Accepting patients

Dose Expansion

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